Aplastic Anemia in Children with Pancytopenia:A Single Center Cross-sectional study from A Tertiary Care Hospital in KPK, Pakistan.
Aplastic Anemia
DOI:
https://doi.org/10.66347/ppj.v50i1.649Keywords:
Pancytopenia, aplastic anaemia, children, bone marrow.Abstract
Abstract: Pancytopenia is decrease in all three cells lines in blood either due to bone marrow failure or peripheral destruction. Aplastic anemia is a rare but concerning cause of pancytopenia in children, which if left untreated can be fatal.
Objective: To determine the frequency of aplastic anemia in children presenting with pancytopenia.
Study Design: Descriptive Cross-Sectional Study.
Place and Duration of Study: Pediatrics Department, Ayub Teaching Hospital, Abbottabad. From January 2020 to June 2020.
Methodology: Non- probability consecutive sampling technique is used and ninety-one children from ages 6 months to 15 years of age of either gender with isolated pancytopenia on admission fulfilling the inclusion criteria were enrolled after informed written consent from the parents. The details of the patients were collected on a predesigned proforma. Data was analysed using SPSS version 20.0.
Results: Total 91 children with pancytopenia were included in this study. The mean age was 4.78±2.33 years. There were 40 (43.9%) children of age <4years while 51 (56.0%) had age >4 years. There were 49(53.8%) males and 42 (46.1%) females. 12 (13.1%) children had aplastic anaemia while 79 (86.3%) had pancytopenia related to other causes.
Conclusion: Aplastic anaemia is a rare but an important treatable cause of pancytopenia in children and by its timely diagnosis and management many lives can be saved and burden on health resources can be minimized.
